Clinical relevance, unmet needs, and implications for personalised care – a review of the current literature

Clinical rationale, current practice gaps, and implications for treatment continuity – a review of the current literature

Individualised dosing is increasingly needed in areas like psychiatry, neurology, paediatrics, and rare diseases, where patient variability and narrow therapeutic windows demand precise dose control. Conventional solid forms come in limited fixed strengths, making it hard for clinicians to fine-tune or titrate doses in small increments.

The Dosage Manager is a handheld device that delivers precise, flexible pellet doses. It targets fields like psychiatry, neurology, paediatrics, rare diseases, and oncology.

Conventional oral solids come in few fixed strengths that prevent fine dose adjustment, which is problematic in paediatric treatment where efficacy must be balanced against side-effects and where swallowing large tablets is hard. This study evaluated the dosing accuracy and precision of an innovative device designed for individualised, flexible dosing of pellet-formulated medicines.